Hugo And Russell's Pharmaceutical Microbiology

Discover the very latest developments in pharmaceutical microbiology in the 9th edition of this popular textbook

Microbiology is one of the essential pharmaceutical sciences upon which the study and practice of pharmacy is built. It has a bearing on all aspects of the manufacture of medicines and sterile products, from their design and development to their delivery as quality products. Few interventions are more central to modern medicine than the treatment of infection, where antibiosis, vaccination and hygienic practices have essential roles to play. The COVID-19 pandemic, the appearance of new pathogens and the rise of antibiotic resistance have demonstrated most completely the need for pharmaceutical practitioners, researchers and industrial scientists to be fully conversant with this field.

The 9th edition of Hugo and Russell’s Pharmaceutical Microbiology has been updated to meet this need. Having long served as the sole comprehensive textbook covering this subject, it has now been adapted to a critical new period in the advancement of medical and pharmaceutical research and development. Its experienced editors have incorporated contributions from subject experts and created a text which will serve the next generation of pharmacy students, pharmaceutical industry scientists and researchers.

In this ninth edition of Hugo and Russell’s Pharmaceutical Microbiology, readers will find:

• A mix of established and new authors bringing practical and research experience to their chapters
• Material covering the fundamentals of microbiology, microbial behavior and laboratory investigation
• Revised chapters incorporating new material on microbe-host interactions, antibiotic resistance, emerging pathogens, public health microbiology, healthcare-associated infection and pharmaceutical manufacture
• Emerging understandings from the COVID-19 pandemic on infection prevention and control and vaccine development
• Practitioners providing their insights on clinical practice and pharmaceutical production
• An accompanying website incorporating teaching resources

Hugo and Russell’s Pharmaceutical Microbiology, 9th edition promises to remain the essential text for pharmacy and medical students, as well as researchers and industry professionals.

Notes on Contributors vii

Preface to the First Edition ix

Preface to the Ninth Edition x

About the Companion Website xi

Part 1 Introducing Pharmaceutical Microbiology 1

1 Introduction to Pharmaceutical Microbiology 3
Brendan F. Gilmore and Stephen P. Denyer

Part 2 Biology of Microorganisms 11

2 Fundamental Features of Microbiology 13
Norman Hodges and Stephen P. Denyer

3 Bacteria 27
David Allison

4 Fungi 47
Kevin Kavanagh

5 Viruses and Other Acellular Infectious Agents: Characteristics and Control 63
Timofey Skvortsov and Jean-Yves Maillard

6 Protozoa 98
Tim Paget

Part 3 Pathogens and Host Response 121

7 Principles of Microbial Pathogenicity and Epidemiology 123
David Allison and Andrew J. McBain

8 Microbial Biofilms: Consequences for Health 135
Brendan F. Gilmore

9 Immunology 147
Mark Gumbleton and Mathew W. Smith

10 Vaccination and Immunisation 174
Gavin J. Humphreys and Andrew J. McBain

Part 4 Prescribing Therapeutics and Infection Control 191

11 Antibiotics and Synthetic Antimicrobial Agents: Their Properties and Uses 193
Brendan F. Gilmore

12 Mechanisms of Action of Antibiotics and Synthetic Anti-infective Agents 232