Casarett & Doull's Essentials Of Toxicology, Fourth Edition

Develop a strong foundation in the concepts and principles of toxicology with this concise and accessible resource

A Doody''s Core Title for 2024 & 2023!

For more than 25 years, Casarett & Doull’s Toxicology: The Basics of Poison has set the standard for providing thorough, academic, and authoritative information in clear and engaging ways. Distilling the major principles and concepts from that renowned text, Casarett & Doull’s Essentials of Toxicology delivers an accessible and highly readable introduction to the science and clinical field of medical toxicology. The book reflects the expertise of more than 60 renowned contributors.

Presented in full-color, this new edition builds on the wide success of previous editions, with extensive updates that make the book more clinically relevant to students and beginners in toxicology, pharmacology, pharmacy, and environmental sciences. Chapter-ending self-assessment Q&As and other features make the learning process more effective and efficient.

Casarett and Doull’s Essentials of Toxicology is organized into seven units:

• General Principles of Toxicology
• Disposition of Toxicants
• Non-organ-directed Toxicity
• Target Organ Toxicity
• Toxic Agents
• Environmental Toxicology
• Applications of Toxicology 

Succinct, yet comprehensive, the text covers essential principles, toxicokinetics, how toxic effects are passed on to succeeding generations, how each body system responds to poisons, and the specific effects of a wide range of toxic agents—from pesticides to radiation.

• Preface
• UNIT 1 GENERAL PRINCIPLES OF TOXICOLOGY
  • 1. The Evolving Journey of Toxicology: A Historical Glimpse
  • 2. Principles of Toxicology
  • 3. Mechanisms of Toxicity
  • 4. Risk Assessment
• UNIT 2 DISPOSITION OF TOXICANTS
  • 5. Absorption, Distribution, and Excretion of Toxicants
  • 6. Biotransformation of Xenobiotics
  • 7. Toxicokinetics
• UNIT 3 NON-ORGAN-DIRECTED TOXICITY
  • 8. Chemical Carcinogenesis
  • 9. Genetic Toxicology
  • 10. Developmental Toxicology
• UNIT 4 TARGET ORGAN TOXICITY
  • 11. Toxic Responses of the Blood
  • 12. Toxic Responses of the Immune System
  • 13. Toxic Responses of the Liver
  • 14. Toxic Responses of the Kidney
  • 15. Toxic Responses of the Respiratory System
  • 16. Toxic Responses of the Nervous System
  • 17. Toxic Responses of the Cornea, Retina, and Central Visual System
  • 18. Toxic Responses of the Heart and Vascular System
  • 19. Toxic Responses of the Skin
  • 20. Toxic Responses of the Endocrine System
  • 21. Toxic Responses of the Reproductive System
• UNIT 5 TOXIC AGENTS
  • 22. Toxic Effects of Pesticides
  • 23. Toxic Effects of Metals
  • 24. Toxic Effects of Solvents and Vapors
  • 25. Toxic Effects of Radiation and Radioactive Materials
  • 26. Toxic Effects of Plants and Animals
  • 27. Food Toxicology: Fundamental and Regulatory Aspects
  • 28. Toxic Effects of Calories
  • 29. Nanoparticle Toxicology
• UNIT 6 ENVIRONMENTAL TOXICOLOGY
  • 30. Ecotoxicology
  • 31. Air Pollution
• UNIT 7 APPLICATIONS OF TOXICOLOGY
  • 32. Analytical and Forensic Toxicology
  • 33. Clinical Toxicology
  • 34. Occupational Toxicology
• Answers to Chapter Questions
• Index