Paul's Fundamental Immunology: Print + Ebook With Multimedia

By (author) Flajnik Martin
Description:
Selected as a Doody''s Core Title for 2025!


Defining the field of immunology for 40 years, Paul’s Fundamental Immunology continues to provide detailed, authoritative, up-to-date information that uniquely bridges the gap between basic immunology and the disease process. The fully revised 8th edition maintains the excellence established by Dr. William E. Paul, who passed away in 2015, and is now under new editorial leadership of Drs. Martin F. Flajnik, Nevil J. Singh, and Steven M. Holland. It’s an ideal reference and gold standard text for graduate students, post-doctoral fellows, basic and clinical immunologists, microbiologists and infectious disease physicians, and any physician treating diseases in which immunologic mechanisms play a role. 

• Reflects the latest advances in the field, including current insights on immune system function, both basic and translational. 

• Contains 50 chapters written by leaders in all subfields of immunology. 

• Provides extensive coverage of the molecular biology that explains the dynamics underlying immune disorders and their treatment. 

• Includes 10 entirely new chapters covering invertebrate and plant immunity, eosinophils, innate lymphoid cells, gamma/delta T cells, NKT and MAIT cells, immunometabolism, maternal-fetal immunology and more. 

• Contains abundant full-color illustrations and tables that provide essential information at a glance. 

• Features annual updates from the authors to the VST version, keeping you current with changes in this dynamic field from the experts. 
   

  Enrich Your eBook Reading Experience 

• Read directly on your preferred device(s), such as computer, tablet, or smartphone. 

• Easily convert to audiobook, powering your content with natural language text-to-speech. 

Table of contents:
Contents
 
Contributors vii
Foreword xiii
Preface xvii
 
Section I. Introduction to Immunology
1 Overview of the Immune System — 1
Martin F. Flajnik, Steven M. Holland, Nevil J. Singh
2 History of Immunology — 29
Edward J. Moticka
 
Section II. Evolution of the Immune System
3 The Insect Immune System — 52
Sara Cherry, Nicolas Buchon
4 Evolution of the Vertebrate and Lower Deuterostome Immune System — 79
Martin F. Flajnik
5 The Plant Immune System — 134
Roger W. Innes
 
Section III. Cellular Pathways and Processes in Immunity
6 Immunometabolism —  161
Jonathan D. Powell, Chirag H. Patel, Im- Hong Sun
7 Regulated Cell Death in the Immune System — 204
Douglas R. Green, Sebastian Ruehl
8 Lymphoid Tissues and Organs — 228
Martin F. Flajnik, Nancy H. Ruddle
9 Type I Cytokines, Interferons, and Their Receptors — 258
Achsah D. Keegan, Warren J. Leonard
10 Tumor Necrosis Factor Superfamily of Cytokines and Receptors — 308
Carl F. Ware, Nancy H. Ruddle
11 Chemokines and Chemokine Receptors — 344
Philip M. Murphy
 
Section IV. Innate Immunity
12 Pattern Recognition Receptors and the IL- 1 Family — 386
Rajendra Karki, Thirumala- Devi Kanneganti
13 The Complement System — 416
Erin E. West, Claudia Kemper
14 Neutrophils — 455
Andres Hidalgo, Mariana J. Kaplan
15 Macrophages — 469
Gwendalyn J. Randolph
16 Mast Cells and Basophils — 487
Mindy Tsai, Stephen J. Galli
17 Eosinophils — 519
Elizabeth A. Jacobsen, Hirohito Kita
18 The